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Year : 2022  |  Volume : 2  |  Issue : 1  |  Page : 40-46

Evaluation of fundus autofluorescence patterns in patients with central serous chorioretinopathy - A prospective, observational study

Department of Retina, Visakha Eye Hospital, Visakhapatnam, Andhra Pradesh, India

Correspondence Address:
Dr. Vasanthi Sannapuri
Department of Retina, Visakha Eye Hospital, Visakhapatnam, Andhra Pradesh - 530 017
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jocr.jocr_7_22

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Aim: The aim of the study was to evaluate the patterns of fundus autofluorescence (FAF) and analyze the association between FAF and swept-source optical coherence tomography (SS-OCT) in idiopathic central serous chorioretinopathy (CSCR). Materials and Methods: 65 eyes of 65 patients were prospectively included in this study. Patients underwent a complete ophthalmologic examination. We classified patterns on FAF imaging into five types as blocked FAF, mottled FAF, hyper-FAF, hyper/hypo-FAF, and descending tract pattern. Each FAF pattern was then analyzed based on the SS-OCT findings. Results: Blocked FAF pattern was seen in 47.69% of patients, mottled in 7.69%, hyper in 23.07%, hyper/hypo in 18.46%, and descending tract in 3.07%. There is a significant difference between FAF patterns in all subjects (P < 0.0001). The blocked FAF pattern (mean [M] = 0.20, standard deviation [SD] = 0.14) showed the best visual acuity among all others. The descending tract FAF pattern group (M = 0.54, SD = 0.08) and hyper/hypo-FAF pattern group (M = 0.38, SD = 0.28) showed the least favorable visual prognosis in our study. The intact ellipsoid zone on the SS-OCT was mostly found in the blocked FAF group, and the disrupted ellipsoid zone was commonly exhibited in the hyper/hypo and descending tract groups. Disrupted external limiting membrane line on the SS-OCT was seen in one patient of the descending tract group only. Conclusions: The association between FAF and SS-OCT findings was analyzed in patients with idiopathic CSCR in our study. Detailed investigation using FAF could help estimate the duration of CSCR.

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